Gelsolin molecular weight
WebJan 25, 2005 · However, when the same concentration of gelsolin was microinjected into BAPTA-AM-treated cells, gelsolin minimally accelerated or slightly slowed disassembly … WebApr 25, 1984 · Gelsolin is an actin-fragmenting cytoplasmic protein. A functionally similar protein has also been identified in plasma. We have compared the structure of the …
Gelsolin molecular weight
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WebOct 10, 1980 · Gelsolin accounts for the majority of Ca2+ control of actin gelation in macrophage extracts. It is a single polypeptide chain with an average molecular weight of 91,000 a Stokes radius of 44 A, a sedimentation coefficient (s20 (0),w) of 4.9 S, an isoelectric point of 6.1, and a frictional ratio of 1.43. WebIn addition to normal sized gelsolin, lower molecular weight fragments were detected; the pattern in Danish heterozygous FAF was similar to that found in heterozygous Finnish patients with the Asn-187 mutation (fig 5). The antibody PoAb 231–242, directed against the amyloid forming region of gelsolin (fig 1) recognised the > 60 kDa gelsolin ...
WebNational Center for Biotechnology Information WebGelsolin is a protein that exerts a variety of influences both within the cytoplasm and in extracellular fluids (reviewed in Yin 1987; Janmey et al. 1998). Intracellular gelsolin …
WebMolecular Weight 85696.935 Theoretical pI 6.19 GO Classification Functions actin binding / calcium ion binding / myosin II binding / protein domain specific binding Processes WebGelsolin, with a mass of 80 kDa, is expressed in all eukaryotes. The name arose from its ability to rapidly dissolve an actin gel and convert it into a soluble form. The N-terminal …
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WebGelsolin definition, an actin-binding protein that modulates actin filament length and gelation, influencing cell locomotion and structure, endocytosis, etc. See more. diamond tours dinner partyWebOct 10, 1980 · It is a single polypeptide chain with an average molecular weight of 91,000 a Stokes radius of 44 A, a sedimentation coefficient (s20 (0),w) of 4.9 S, an isoelectric … diamond tours from michiganWebFeb 23, 2024 · Gelsolin is a protein of the gelsolin superfamily. It is encoded by the gelsolin gene located on the human chromosome 9 [ 8 ]. It is a highly conserved, multifunctional actin-binding protein first described in the cytosol of macrophages and later in many other cells [ 9 ]. diamond t outfitters mount pleasant texasWebApr 1, 2024 · Tandem mass spectrometry analysis identified the 80 kDa co-precipitating protein as Gelsolin and the 210 kDa co-precipitating protein as a high molecular weight form of myosin light chain kinase ... diamond towel and supply llcWebMay 1, 1984 · These features of GSN have an important impact on cell shape, chemotaxis, and secretion [38, 39]. GSN is encoded on chromosome 9 in humans, and its molecular weight ranges from 82-85 kDa. ... c# is not null hereWebApr 10, 2024 · Korkmaz et al. generated new small molecular weight amino benzohydroxamic acid derivatives which exhibited potent antiproliferative effects on HeLa cells and suppressed glutathione reductase and ... Eun et al. showed that apicidin mediates gelsolin induction in HeLa cells via the protein kinase C (PKC) signaling pathway, and … c# is not null checkWebGelsolin (actin-depolymerizing factor, ADF, AGEL, Brevin) is an 83 kDa protein that shares structural and functional homology to villin and adseverin/scinderin (1,2). Gelsolin plays an important role in actin filament assembly by capping and severing actin proteins in a Ca … diamond tours trip advisor canadian maritmes