Siglectf
WebCD170, also known as Siglec-F, Siglec-5, is a member of the Sialic acid-binding Ig-like lectin family, type I single pass transmembrane protein, with 4 extracellular Ig-like domains and … WebWe analyzed mouse BAL cells by flow cytometry using antibodies against Siglec-F, F4/80 and CD11b. Next to the Siglec-F positive eosinophils and the F4/80 positive macrophages, …
Siglectf
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WebApr 10, 2024 · The emerging importance of the Siglec-sialic acid axis in human disease, especially cancer, has necessitated the identification of ligands for Siglecs. Recombinant Siglec-Fc fusion proteins have been widely used as ligand detectors, and also as sialic acid-targeted antibody-like proteins for cancer treatment. However, the heterogenetic … WebThrough binding ubiquitous sialic-acid residues on cell surfaces, the Siglec family of lectins promote cell–cell interactions and regulate the functions of numerous immune-cell types. …
WebSIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is expressed … WebDescription: This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds …
Web表达区间及表达系统（Source）. Alexa Fluor 488-Labeled Human Siglec-2, His Tag (SI2-HA2H7) is produced via conjugation of AF488 to Human Siglec-2, His Tag with a new generation site-specific technology under Star Staining labeling platform. Human Siglec-2, His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg ... WebOct 7, 2016 · Here, using a monoclonal antibody we generated to the Sialic acid-binding immunoglobulin-like lectin F (Siglec-F), we show that Siglec-F is expressed on mouse M …
WebJun 22, 2005 · Analysis of sialoside specificity of Siglec-F. To understand the structural requirement of 6′-sulfo-sLe X that confers increased affinity to Siglec-F, we further verified the glycan array results by reverse assay using various sialylated oligosaccharides coupled to polyacrylamide backbones (sialoside-PAA probes) and immobilized Siglec-F-Fc chimera.
WebThe important finding that deleting Mo-AMs within an injured lung can lessen the severity of fibrosis represents a significant advance in the field (14 and 15).Although many groups have shown that mice with systemic monocytopenia (i.e., mice given intravenous liposomal clodronate, CCR2 −/− mice, and CEPBδ −/− mice) are protected against fibrosis (8, 16, 17), … 19美金 台幣Siglecs are Type I transmembrane proteins where the NH3 -terminus is in the extracellular space and the COO -terminus is cytosolic. Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid. These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold. All Siglecs are extended … 19美元 人民币WebIn recent years multi-parameter flow cytometry has enabled identification of cells at major stages in myeloid development; from pluripotent hematopoietic stem cells, through … 19美金等于多少人名币WebSiglecs are cell surface lectins that recognize sialic acids and are primarily expressed in hematopoietic cells. Previous studies showed that some Siglecs regulate macrophage … 19美元等于多少人民币WebDendritic cells (DCs) are among the first cells that recognize incoming viruses at the mucosal portals of entry. Initial interaction between DCs and viruses facilitates cell activation and migration to secondary lymphoid tissues, where these antigen presenting cells (APCs) prime specific adaptive immune responses. Some viruses, however, have … 19翻译成英文WebOct 5, 2024 · Eosinophil recruitment in asthma is a multistep process, involving both trans-endothelial migration to the lung interstitium and trans-epithelial migration into the … 19美金 人民币19美元多少钱